Minimal alveolar concentration of sevoflurane for induction of isoelectric electroencephalogram in middle-aged adults

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Minimal alveolar concentration of sevoflurane for induction of isoelectric electroencephalogram in middle-aged adults.

BACKGROUND We determined the minimal alveolar concentration (MAC) of sevoflurane inducing an isoelectric EEG in 50% of adult subjects (MACie). METHODS We included 31 middle-aged subjects; 30 subjects finished the study protocol and received sevoflurane at preselected concentrations according to a modified Dixon 'up-and-down' design starting at 1.7 vol% with 0.2 vol% steps size. General anaest...

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 2014

ISSN: 0007-0912

DOI: 10.1093/bja/aet280